The news of Syracuse and Pitt moving to the ACC will keep the whole conference realignment merry-go-round going and may increase the chance that YSU's affiliation is affected.
From a football perspective, I don't see much happening to the MVFC. I think the only way that YSU is impacted from a football perspective is when the day comes that the really big boys decide to take their ball away from the NCAA and tell the big time football wannabes to hit the road. Now what the prospect of 4 16-team superconferences does to the our blood money games, remains to be seen.
I think the breakup of the Big East could have an impact on the Horizon League. If enough of the Big East football playing schools bolt for the ACC to cause the demise of the Big East, the basketball realignment that is sure to follow "could" have an impact.
Logically Butler would seem to be attractive if schools like Marquette and DePaul are looking for new affiliation. While Butler basketball certainly is attractive, I don't know if they have the cash to put all of their sports on the big boy level. I suspect Butler's ability to raise the athletic budget up to the levels needed to participate at the level are similar to the challenges YSU has in trying to just get to the MAC level.
Going to be interesting to watch. We should try to use this thread to post any articles that get down to the Horizon League level of discussion.